A recent study has shown that lycopene, a natural plant extract found in tomatoes and other fruits, may have a positive impact on brain function in mice exhibiting depressive symptoms.
Researchers divided 60 mice with depressive behaviors into two groups. The first group received 20 mg of lycopene per kilogram of body weight, while the second group received a placebo. The results indicated that the mice who ingested lycopene displayed increased sociability, curiosity, and optimism. Additionally, lycopene appeared to enhance their synaptic plasticity, which plays a crucial role in memory and learning.
The researchers highlighted the potential benefits of natural plant extracts compared to synthetic medications, emphasizing their long-term safety and fewer side effects. They noted that lycopene, being widely accessible and possessing potent antioxidant properties, holds promise as a potential therapeutic agent.
However, the study's findings may not be directly applicable to humans due to the significant dose of lycopene administered to the mice. The equivalent dose for a 90 kg human would be 147 mg, exceeding the recommended daily intake of 75 mg. While a 2024 study indicated no specific risks associated with higher lycopene consumption, researchers are proceeding cautiously in this area to ensure safety.